2009-04-22 12:00:00

Gilead Patent US8008264B2 filed

Application filed by Gilead Sciences Inc "1′-substituted carba-nucleoside analogs for antiviral treatment" : Patent claims remdesivir’s molecular structure Patent listed in Gilead Sciences’ new drug application for Veklury

2009-07-07 12:00:00

Remdesivir (then GS-5735) was originally created and developed by Gilead Sciences in 2009, to treat hepatitis C and respiratory syncytial virus (RSV)

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2015-06-15 05:53:53

China MIL77 (based on ZMapp) success against Ebola

They included MIL77, a product from China that was also given to a British Army nurse who recovered from Ebola at a London hospital in March. Note - USA (BARDA / Robinson) object

2016-03-10 12:00:00

*Gain-of-Function Symposium 2016

Present : Michael Callahan, Ralph Baric

2016-03-17 22:32:55

*Baric - WIV-COV has pandemic potential

Also in a research paper (a research paper that was in the "DEFUSE PROPOSAL" research files) : SARS-likeW IV1-CoVp oisedf or humane mergence Vineet D. Menachery8 • Boyd L. Yount Jr.•. Amy C. Sims8 , Kari Debbink•·b, Sudhakar S. Agnihothram<, Lisa E. Gralinski", RachelL . Graham•, Trevor Scobey•, JessicaA . Plante•. Scott R. Royal",J esicaS wanstrom•, Timothy P. Sheahan•, Raymond J. Pickles<.dD, avide Corti0 • 1•9, Scott H. Randelld, Antonio Lanzavecchia0 • 1, Wayne A. Marascoh, and Ralph s. Banc••c1. •Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599; •Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599; 'Division of Microbiology, National Center for Toxicological Research, Food and Drug Administration, Jefferson, AR 72079; •Department of Cell Biology and Physiology and Marsico Lung lnstitute/9.'stic Fibrosis Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599; 'Institute for Research in Biomedicine, Bellinzona, Switzerland; Institute of Microbiology, EidgenOssische Technische Hochschule Zurich. Zurich, Switzerland; 9Humabs BioMed SA. Bellinzona, Switzerland; and hDepartment of Cancer Immunology and AIDS, Dana-Farber Cancer Institute-Department of Medicine, Harvard Medical School, Boston MA 02215 Edited by Peter Polese, lcohn School of Medicine ot Mount Sinoi, New York, NY, and approved January 6, 2016 (received for review September 4, 2015) Mentions ZMapp could be a good treatment !

2016-11-10 12:00:00

Trump wins US Presidential election

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2016-11-12 12:00:00

*WHO declares end to Zika pandemic

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2016-11-15 12:00:00

*Rick Bright repleaces Robin Robinson as BARDA lead

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2016-12-08 12:00:00

21st Century CURES act passed by congress

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2016-12-13 12:00:00

21st Century CURES act signed into law

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2017-01-10 12:00:00

*Fauci (Georgetown event) - Next admin will have "surprise" pandemic

NOTE: Fauci talks about "pandemic preparedness" ... and CEPI (Coalition for Epidemic Preparedness) is launched the following week ..,

2017-01-17 12:00:00


2017-01-18 12:00:00

*CEPI launched (Farrar, R.Katz, Bright)

A global coalition to create new vaccines for emerging infectious diseases launched Wednesday with the ambitious aim of protecting the world from future epidemics. Announced at the World Economic Forum in Davos, Switzerland, the initiative has an initial investment of nearly $500 million from the Bill and Melinda Gates Foundation, Britain’s Wellcome Trust and the governments of Japan, Norway and Germany. The partnership will be called the Coalition for Epidemic Preparedness Innovations, or CEPI. It grew out of the lessons from the world’s woeful lack of preparedness for the 2014 Ebola epidemic in West Africa, which killed more than 11,000 people and caused at least $2.2 billion in economic losses in the three hardest-hit countries. As a result of that and the current Zika epidemic in the Americas, a global consensus has steadily grown among an array of governments, public health leaders, scientists and vaccine industry executives that a new system is needed to guard against future health threats. Global health experts welcomed the initiative, saying it would complement efforts already underway by the World Health Organization and the U.S. Biomedical Advanced Research and Development Authority (BARDA), part of the Department of Health and Human Services, which are working on Ebola and Zika vaccines. The United States is not providing funding for CEPI, but it is offering subject expertise. Officials took part in the planning discussions, and “while we are not a formal partner to CEPI, we foresee synergies between our approaches,” BARDA Director [Dr. Rick Arthur -Bright (born 1966)] said in a statement. One such area is development of the most efficient technology for biodefense and infectious disease response, he said. [Dr. Rebecca Lynn Katz (born 1973)], director of Georgetown University’s Center for Global Health Science and Security, expects the new coalition “will just add much needed resources to a hard problem” and not detract from other efforts' funding and resources.

2017-01-20 12:00:00

Trump Presidency begins

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2019-02-07 12:00:00

*Bavari, Totura: "Coronavirus antiviral drug discover paper" accepted

"Broad-spectrum coronavirus antiviral drug discovery" * Mentions bat source and food market ("The intermediate hosts during the 2003 SARS-CoV epidemic included civets and other small carnivore species located in wet animal markets.") * Mentions GS-5734 as most likely antiviral that will work

2019-03-14 12:00:00

USAMRIID announced FDA will allow animal model to develop Remdesivir

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2019-04-16 12:00:00

USAMRIID, 22M project awarded to develop antibody based therapies for 4 lethal viruses

2019-05-24 12:00:00

Canada NML violation reported by RCMP

HITS Research :

2019-07-05 12:00:00

*Heinz Feldmann: Doubts X Qiu arrest related to ZMapp

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2019-07-05 12:00:00

*Xiangguo Qiu escorted out of lab; not seen since

2019-07-16 12:00:00

Ft. Detrick shutdown: The CDC sent a cease and desist order in July.


2019-08-14 12:00:00

WHO: 2 ebola drugs move forward , 2 dont (Remdesivir/ZMapp) NIAID mAb114 , REGN-EB3 But not - ZMapp or Remdesivir

2019-09-17 12:00:00

Sina Bavari leaves USAMRIID, starts consulting firm

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2019-09-24 07:54:27

Modernizing Influenza Vaccines in the United States to Promote National Security and Public Health

2019-09-29 12:00:00

*Zantac Pulled From Shelves Over Carcinogen Fears

2019 (Sep 30) - Related ?? NYTimes : "Zantac Pulled From Shelves by Walgreens, Rite Aid and CVS Over Carcinogen Fears" The pharmacy chains are pulling the heartburn medication from shelves after the Food and Drug Administration warned that it had detected low levels of a cancer-causing chemical in samples of the drug. NOTE - ranitidine bismuth citrate later found to be powerful in COVID treatments ...See

2019-10-17 12:00:00

*Daszak/Olival in China collecting viruses from rat farm

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2019-10-18 12:00:00

Event 201 (Rick Bright attends)

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2019-10-24 12:00:00

*US gov announced EcoHealth budget cuts

2019 (Oct 25) - NYTimes - "Scientists Were Hunting for the Next Ebola. Now the U.S. Has Cut Off Their Funding." Predict, a government research program, sought to identify animal viruses that might infect humans and to head off new pandemics. Mentioned : Dr. Dennis Thomas Carroll (born 1948) / Dr. Peter Daszak (born 1965) /

2019-10-29 12:00:00

*Milken Univ Flu Vaccine Panel - Rick Bright needs "excitement"

Watch here :

2019-11-01 13:58:23

Kadlec optimistic of EID-2801 for SNS, Bright doubtful

Even before the presentation began, Dr. Kadlec indicated his enthusiasm for EIDD-2801’s potential. Observing Dr. Bright’s skepticism during the presentation, Dr. Kadlec asked him why he was not similarly excited. Dr. Bright responded that he was excited about the potential of any promising new drug, but he knew that similar drugs produced fetal abnormalities, and his priority was to ensure drug safety. Unwilling to support a potentially toxic and harmful drug without further data

2019-11-27 12:00:00

*Olival (EcoHealth) on Fox news Kennedy nation

Video :

2019-12-09 12:00:00

*Nipah Conference Singapore

Present : P Daszak / E de Wit / H Feldmann / Richard Hatchett (CEPI CEO) / Zhengli Shi (WIV), Hilary Marston (Fauci's admin assistant), De Wit session - "Therapeutic remdesivir treatment protects African green monkeys from lethal Nipah virus, Bangladesh challenge Dr. Emmie de Wit, Laboratory of Virology, NIAID, NIH" .. **** Notes from this presentation are not available. ****

2019-12-10 12:00:00

*Daszak interview by TWIV

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2020-01-02 12:00:00

*WIV researchers confirm whole genome sequence of 2019-nCoV

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2020-01-04 12:00:00

*Callahan ph Malone: famotidine may help CV19

Source : "The Real Anthony Fauci" RFK Jr. book (2021) - Download the full PDF here : [HB0078 which is] "During his January 4 phone call, Callahan told Malone that he was just outside Wuhan. Malone assumed that Callahan was visiting China under cover of his Harvard and Massachusetts General Hospital appointments. Callahan told Malone that he had been treating “hundreds” of COVID-19 patients. Callahan subsequently described to National Geographic how he had pored through thousands of case studies at the outbreak’s epicenter. He giddily reported his amazement at the virus’s “magnificent infectivity,” and its capacity to explode “like a silent smart bomb in your community.”91"

2020-01-09 12:00:00

*DTRA DOMANE computers - RemD, Ivm, HCQ may all help with CV19

Date estimated...

2020-01-10 12:00:00

*Gilead has 5000-patient RemD supply in storage

Jan 10 : Thanks to its work on Ebola, Gilead already had a small supply of remdesivir on hand. Sitting in cold storage in Switzerland and California, were enough 30-milliliter vials of the drug to treat 5,000 people, which made it possible to begin human trials in the U.S., China, and elsewhere. Bloomberg - Archived version :

2020-01-12 12:00:00

Li Wenliang was admitted to intensive care at Houhu Hospital District, Wuhan Central Hospital,[30] where he was quarantined and treated

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2020-01-15 12:00:00

*Snohomish County Man arrives in USA, back from Wuhan

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2020-01-21 12:00:00

*Snohomish County: 1st CV19 USA case iannounced CDC / Katz / Messonnier

Info presented by Nancy Messonnier, and Rebecca Katz (Note - Rebecca Katz is a frequent collaborator of Rick Bright)

2020-01-23 00:19:16

*Peter Salama death (was WHO #2), Age 52

2020-01-23 12:00:00

*Inovio, Moderna get CEPI funds for CV19 vx wiork

"Inovio, Moderna score CEPI funding for vaccine work against deadly coronavirus"

2020-01-25 12:00:00

*Rcvd ZL Shi pub: RemD and HCQ may help CV19

Jan 25 2020 / ONLINE pub Feb 04

2020-01-25 12:00:00

*RemD treatment starts for Snohomish County Man

Jan 25 - Compassionate use ! Not made public until Feb 01

2020-01-28 12:00:00

Charles Lieber arrest

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2020-01-30 12:00:00

*China: RemD, Chloroquine and Ritonavir potentially effective vs SARSCOV2

Jan 30 (Xinhuanet)

2020-01-30 12:00:00

*Snohomish Cty Man near full recovery "thanks to Remdesivir"

Note - this is not announced until later... it is still not official within the USA that Remdesivir is being used here

2020-01-30 12:00:00

*Gilead restarts factory in Edmonton

Jan 30 (est, could be earlier): In January 2020, Gilead began working on restarting remdesivir production in glass-lined steel chemical reactors at its manufacturing plant in Edmonton, Alberta.[47] The Edmonton plant also had enough raw materials to start on another batch of powder in its glass-lined steel reactors. This batch, enough for at least 30,000 patients, was completed by early April.

2020-01-30 12:00:00

*Gilead orders RemD compounds from CHina

*Jan 30 (est, could be earlier): So back in January it ordered more than a dozen of the most crucial starting materials and reagents from suppliers in China, Europe, and elsewhere. Gilead also helped its contractors locate sufficient supplies of compounds needed to make those starting materials. Archived locally :

2020-01-31 12:00:00

India Paper "Uncanny similarity of unique inserts in the 2019-nCoV spike protein to HIV-1 gp120 and Gag"

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