See the similarities and differences in plant epigenomics.
Small RNAs act in processes such as mRNA destruction, translational inhibition, and DNA methylation. Now it appears that, at least in plants, small RNAs are also involved in DNA demethylation.
Conventional wisdom had it that once a methylated repeat sequence is heavily demethylated, there’s no turning back. Not only don’t they become remethylated, but subsequent generations inherit the epigenetic changes as well. But a group of European researchers have found that this isn’t always the case.
Researchers report that RNA interference (RNAi) machinery can remethylate target sequences that were hypomethylated by mutation of the chromatin remodeler gene DDM1.
Researchers report on how plants use their diverse small RNA repertoires. Whereas miRNAs’ effects are limited to one or a few cells, tasiRNAs have a much wider audience.
Researchers describe potential pitfalls of sodium bisulfite sequencing in plants and share some helpful tips.
A team of scientists at UC Riverside came across RDM1 while screening for gene mutations that play a role in the DNA methylation of certain loci, and regulate TGS. A few experiments later, they found out a lot more about their new puzzle piece.
At the onset of winter, plants in temperate regions, such as Arabidopsis thaliana, undergo a process called vernalization where they prep to quickly flower once spring rolls back around. Researchers demonstrate that vernalization in Arabidopsis involves some serious histone methylation that’s orchestrated by a string of RNA.
Plants not only remember that they went through a cold period, but they also remember how long it lasted. Enduring a cold period, or vernalization, makes plants competent to flower when they finally experience the warmth of spring, and as it turns out one of our favorite repressive histone mods, H3K27me3, is at the heart of it all.
Researchers report that intronic RNAs usher the repressive polycomb complex right to the specific chromatin regions they need to target in order to repress epigenetic genes in a human cancer cell line
Life is tough out there for a plant; So evolution has given plants a little gift to cope: Epigenetics.
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